Born and raised in New York city, Sam Besca has been acting in plays and films from the age of eight years old. She had her off-broadway debut in B.O.T.C.H. in 2009 and was nominated for a National Youth Arts Award for her performance. She was also nominated in 2014 for her performance as Veronica Venus in Samantha Spade.

She is currently acting and directing in New York City.