Derpixon is an animator and artist best known for adult-oriented and Rule 34 content. Often compared to other online animators such as ZONE-Tan and Minus8, Derpixon has content of varying lengths from single pictures, loops and up to full 11-minute-plus videos. Most of her material can be found on Newgrounds where she have resided since 2015. Several of Derpixon's animations have gone viral over the years and often inspired memes, including FandelTales, Party Games and Mime and Dash. In February 2025, Derpixon announced an indefinite hiatus from animating.