Lili Anne Taylor (born February 20, 1967) is an American actress. She came to prominence with supporting parts in the films Mystic Pizza (1988) and Say Anything... (1989), before establishing herself as one of the key figures of 1990s independent cinema through starring roles in Bright Angel (1990), Dogfight (1991), Household Saints, Short Cuts (both 1993), The Addiction (1995), I Shot Andy Warhol (1996), and Pecker (1998). Taylor is the recipient of four Independent Spirit nominations, winning once in the category of Best Supporting Female.

Alongside her work on smaller-scale projects, Taylor has encountered mainstream success with parts in films such as Born on the Fourth of July (1989), Rudy (1993), Ransom (1996), High Fidelity (2000), Public Enemies (2009), The Conjuring (2013), and Maze Runner: The Scorch Trials (2015). Other credits include The Notorious Bettie Page (2005), To the Bone (2017), and Paper Spiders (2020).

Outside of film, Taylor has appeared in an array of television series. She was nominated for a Primetime Emmy for Outstanding Lead Actress award for portraying Anne Blaine on American Crime (2015–2017). She received two more Emmy nominations for her guest role as Marty Glenn on The X-Files (1998) episode "Mind's Eye" and for her recurring role as Lisa Kimmel on Six Feet Under (2002–2005). Taylor's stage credits include Broadway productions of Anton Chekhov's Three Sisters (1997) and Scott McPherson's Marvin's Room (2017).