Fred Roy Harris (November 13, 1930 – November 23, 2024) was an American politician from Oklahoma who served from 1957 to 1964 as a member of the Oklahoma Senate and from 1964 to 1973 as a member of the United States Senate.

Harris was elected to the Oklahoma Senate after graduating from the University of Oklahoma College of Law. He ousted the appointed U.S. Senate incumbent, J. Howard Edmondson, and won a 1964 special election to finish Robert S. Kerr's term, narrowly defeating football coach Bud Wilkinson. Harris strongly supported the Great Society programs and criticized President Lyndon B. Johnson's handling of the Vietnam War. He was reelected in 1966 and declined to seek another term in 1972.

From 1969 to 1970, Harris chaired the Democratic National Committee. In the 1968 presidential election, Democratic nominee Hubert Humphrey strongly considered him as his running mate. Harris unsuccessfully sought the Democratic presidential nomination in 1972 and 1976. After 1976, he was a professor at the University of New Mexico.