George Angelopoulos graduated from the Film School of Fine Arts of the Aristotle University of Thessaloniki, specializing in Directing.

He then obtained a Master's degree in Screenwriting from the University of The Arts, London, on a scholarship.

In 2017, he began working at the Development and Production Directorate of the Hellenic Film Center, for which he assumed the duties of Director in 2020. He put into effect a new modern Regulation of funding programs with a provision for the immediate absorption of young professionals into work and incentives that encouraged inclusivity among the contributors of short films.

During his tenure, the evaluation mechanism was formed with a register of readers and clear artistic criteria, and hundreds of film projects at the writing, development and production stages were funded.

He has been active in adult film education and participated in the creation and implementation of the Script Development workshop for Children and Youth Films of the Olympia International Film Festival.

He is an external expert of the Creative Europe MEDIA Office and has contributed as a script consultant to short and feature films.

The Goldfish (2017), his first short film as a screenwriter-director, had its international premiere at BFI Flare and was subsequently part of the British Council's International Campaign for Equality and Human Rights.

In 2025 he completed his second short film.