Liana Orfanou was born in 1932 in Thessaloniki and studied at the drama school of the Greek and National conservatories (Mihali Kounelaki and Thanou Traga, respectively).

In 1952 she made her theatrical debut in the revue, "Star Hellas". Afterwards, he played in many reviews: "The Song of Athens", "Carnation in the Ear", "Coca Cola" etc. In 1955 she participated in beauty pageants and on June 18, 1956 she enrolled in S.E.H.

In the 1960s he collaborated with many troupes: Kostas Maniatakis - Mairis Vassilakis, Kostas Hatzichristou, Katerinas Andreadis, Christou Efthymiou - Renas Vlachopoulos, Lamprou Zounis, etc. From 1966 she created her own troupes, while also touring the United States.

Liana Orfanou played in 11 films: "Prio pantos composure", "The Crooked Wood", "Golfo", "I want you to live mother", "The Square's Daughter", "The Master's Lady", "The Municipality of Trikala", "Crying Bridegroom", "On the Sidewalk", "The Bullfighter Goes On!" and "The Children of Maddalena".

He has been dead for many years (we don't know the exact date).